To help reduce withdrawal, your health care provider could lessen your dose slowly. Withdrawal is much more probably When you've got employed this medication for many years (quite a lot of weeks) or in superior doses. Tell your medical professional or pharmacist at once Should you have withdrawal.
Warning ought to be exercised when promethazine hydrochloride and codeine phosphate syrup is administered to a nursing lady.
Explain to your doctor In case your cough lasts, returns, or gets even worse after 7 times or whether it is accompanied by headache that does not go away, fever, critical sore throat, or rash.
Drop off any unused narcotic drugs at a drug just take-again area at once. If you don't Have a very drug consider-back location near you, flush any unused narcotic drugs down the bathroom.
Promethazine needs to be employed cautiously in persons with heart problems or with impairment of liver functionality.
Instruct nursing mothers to talk to the newborn’s physician straight away when they observe these symptoms and, if they can not get to the health practitioner right away, to go ahead and take toddler to an crisis area or get in touch with 911 (or community crisis companies).
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Excessively massive dosages of antihistamines, which includes promethazine hydrochloride, in pediatric individuals may perhaps result in unexpected death (see OVERDOSAGE). Hallucinations and convulsions have happened with therapeutic doses and overdoses of promethazine hydrochloride in pediatric people. In pediatric individuals who're acutely unwell associated with Promethazine codeine syrup dehydration, You can find a heightened susceptibility to dystonias with the usage of promethazine HCl.
Bone-Marrow Despair – Promethazine must be applied with warning in patients with bone-marrow melancholy. Leukopenia and agranulocytosis are already noted, normally when promethazine HCl is used in Affiliation with other recognized marrow-harmful brokers.
Codeine: Dosage of codeine SHOULD NOT BE Greater if cough fails to respond; an unresponsive cough should be reevaluated in 5 days or sooner for attainable underlying pathology, for instance foreign body or reduce respiratory tract sickness.
Bronchial asthma Along with other Respiratory Problems: Narcotic analgesics or cough suppressants, such as codeine, should not be used in asthmatic clients (see CONTRAINDICATIONS). Nor must they be Employed in acute febrile disease linked to productive cough or in chronic respiratory condition exactly where interference with capacity to clear the tracheobronchial tree of secretions might have a deleterious impact on the client’s respiratory perform. Hypotensive Effect: Codeine might produce orthostatic hypotension in ambulatory patients.
Anticholinergics - Concomitant use of other brokers with anticholinergic Qualities must be undertaken with caution.
In Yet another analyze a single one hundred-mg/kg dose of codeine administered to Expecting mice reportedly resulted in delayed ossification inside the offspring.
Take into account that this medication continues to be prescribed since your physician has judged which the advantage to you personally is greater than the risk of side effects. Many of us employing this medication do not have major Unintended effects.